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Nacional 900 833 933
Internacional +34 93 285 82 16
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Complementary techniques Assisted reproduction

ICSI
(Sperm microinjection)

What is ICSI?

ICSI, which stands for intracytoplasmic sperm injection, is a procedure developed in 1992 in which a single sperm is injected directly into an egg using a fine needle. Unlike conventional In Vitro Fertilisation (where the sperm and egg are incubated together to allow fertilisation to occur), IVF with ICSI achieves fertilisation through direct sperm injection.

This technique was created to allow men with a very low sperm count or poor motility to avoid resorting to sperm donation. Currently, it is indicated in most IVF treatments. Currently, it is indicated in most In Vitro Fertilization treatments.

Contents

What are the main indications for using ICSI?

  • Cases of male factor infertility: men with reduced sperm concentration or motility. . With this diagnosis, the chances of success with conventional IVF are low.
  • Cases with fertilisation failure in previous conventional IVF procedures.
  • Cases with valuable sperm samples, such as frozen sperm in cancer patients and vasectomised men.
  • When sperm is obtained directly from the testicle, whether due to the obstruction of the vas deferens, absence of these ducts, problems with ejaculation, etc.
  • Infectious diseases in men, such as HIV or hepatitis B or C, where there would be an increased risk of infection for the partner if conventional IVF were performed.
  • A relative indication would be a low number of eggs retrieved in ovarian stimulation.

Frequently Asked Questions About ICSI

ICSI can only be performed when the eggs are mature, meaning, when they are at the optimal moment for fertilisation. This represents only a portion of the total eggs retrieved in a cycle. There are poor-quality eggs that are damaged at the time of sperm injection.

From the good-quality eggs, fertilisation is usually achieved in about 70 % of cases.

The results of embryo quality in ICSI and conventional IVF are usually comparable. Some experts believe that manipulation of the egg can alter embryo quality. However, this risk is minimal when performed by an expert biologist.

In cases of severe male factor infertility, before performing IVF with sperm microinjection, it is important to conduct a study of testicular meiosis to rule out genetic abnormalities in the sperm that could lead to repeated failures in achieving pregnancy or embryonic abnormalities. In some cases, if there are enough spermatogenesis cells, this study can be done on the sperm

Other Complementary Techniques

Increase your chances of pregnancy even more with the most appropriate complementary techniques for your treatment.